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BDBM50275258 CHEMBL520857::[3,5-Dimethoxy-4-(4'-hydroxy-3'-isopropylbenzyl)phenoxy]methylphosphonicAcid

SMILES: COc1cc(OCP(O)(O)=O)cc(OC)c1Cc1ccc(O)c(c1)C(C)C

InChI Key: InChIKey=XPRFBHXIZHHZHD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275258   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thyroid hormone receptor beta


(Homo sapiens (Human))
BDBM50275258
PNG
(CHEMBL520857 | [3,5-Dimethoxy-4-(4'-hydroxy-3'-iso...)
Show SMILES COc1cc(OCP(O)(O)=O)cc(OC)c1Cc1ccc(O)c(c1)C(C)C
Show InChI InChI=1S/C19H25O7P/c1-12(2)15-7-13(5-6-17(15)20)8-16-18(24-3)9-14(10-19(16)25-4)26-11-27(21,22)23/h5-7,9-10,12,20H,8,11H2,1-4H3,(H2,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
146n/an/an/an/an/an/an/an/a



Metabasis Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]3,5,3'-triiodo-L-thyronine His-tagged human recombinant TRbeta1 by scintillation proximity assay


J Med Chem 51: 7075-93 (2009)


Article DOI: 10.1021/jm800824d
BindingDB Entry DOI: 10.7270/Q21V5DT5
More data for this
Ligand-Target Pair
Thyroid hormone receptor alpha


(Homo sapiens (Human))
BDBM50275258
PNG
(CHEMBL520857 | [3,5-Dimethoxy-4-(4'-hydroxy-3'-iso...)
Show SMILES COc1cc(OCP(O)(O)=O)cc(OC)c1Cc1ccc(O)c(c1)C(C)C
Show InChI InChI=1S/C19H25O7P/c1-12(2)15-7-13(5-6-17(15)20)8-16-18(24-3)9-14(10-19(16)25-4)26-11-27(21,22)23/h5-7,9-10,12,20H,8,11H2,1-4H3,(H2,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
3.30E+3n/an/an/an/an/an/an/an/a



Metabasis Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assay


J Med Chem 51: 7075-93 (2009)


Article DOI: 10.1021/jm800824d
BindingDB Entry DOI: 10.7270/Q21V5DT5
More data for this
Ligand-Target Pair