BDBM50275551 2-(4-fluorophenyl)-7-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine::CHEMBL487780

SMILES: Cc1cccc2c(c(nn12)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=TULDMBUASKXWQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50275551 (2-(4-fluorophenyl)-7-methyl-3-(pyridin-4-yl)pyrazo...) Show SMILES Cc1cccc2c(c(nn12)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C19H14FN3/c1-13-3-2-4-17-18(14-9-11-21-12-10-14)19(22-23(13)17)15-5-7-16(20)8-6-15/h2-12H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coli				Bioorg Med Chem Lett 18: 5428-30 (2008) Article DOI: 10.1016/j.bmcl.2008.09.040 BindingDB Entry DOI: 10.7270/Q27S7NM9
					More data for this Ligand-Target Pair