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BDBM50275579 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile::CHEMBL488183

SMILES: Fc1ccc(cc1)-c1nn2cc(ccc2c1-c1ccncc1)C#N

InChI Key: InChIKey=LQQPWBQKAOPXPO-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275579   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50275579
PNG
(2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]...)
Show SMILES Fc1ccc(cc1)-c1nn2cc(ccc2c1-c1ccncc1)C#N
Show InChI InChI=1S/C19H11FN4/c20-16-4-2-15(3-5-16)19-18(14-7-9-22-10-8-14)17-6-1-13(11-21)12-24(17)23-19/h1-10,12H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 140n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coli


Bioorg Med Chem Lett 18: 5428-30 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.040
BindingDB Entry DOI: 10.7270/Q27S7NM9
More data for this
Ligand-Target Pair