BDBM50275622 CHEMBL487154::N,N'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)dibenzamide

SMILES: O=C(Nc1nc(NC(=O)c2ccccc2)n(n1)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=GFQQPQUENQSFFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50275622 (CHEMBL487154 | N,N'-(1-phenyl-1H-1,2,4-triazole-3,...) Show SMILES O=C(Nc1nc(NC(=O)c2ccccc2)n(n1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H17N5O2/c28-19(16-10-4-1-5-11-16)23-21-25-22(24-20(29)17-12-6-2-7-13-17)27(26-21)18-14-8-3-9-15-18/h1-15H,(H2,23,24,25,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of recombinant ERK2 (unknown origin)				Bioorg Med Chem Lett 18: 5372-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.058 BindingDB Entry DOI: 10.7270/Q2J38SC3
					More data for this Ligand-Target Pair