BDBM50275807 mannose 6-phosphate
SMILES: O[C@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O
InChI Key: InChIKey=NBSCHQHZLSJFNQ-PQMKYFCFSA-M
Data: 2 IC50
PDB links: 15 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50275807 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cation-dependent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50275807
(mannose 6-phosphate)Show SMILES O[C@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/p-1/t2-,3-,4+,5+,6+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 2 et 1
Curated by ChEMBL
| Assay Description Binding affinity to CI-M6PR |
Bioorg Med Chem Lett 18: 6240-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.09.101 BindingDB Entry DOI: 10.7270/Q2WD41HG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cation-independent mannose-6-phosphate receptor
(Homo sapiens (Human)) | BDBM50275807
(mannose 6-phosphate)Show SMILES O[C@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/p-1/t2-,3-,4+,5+,6+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by ChEMBL
| Assay Description Displacement of pentamannosyl phosphate bovine serum albumin from M6P/IGF2R |
Bioorg Med Chem Lett 18: 3085-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.094 BindingDB Entry DOI: 10.7270/Q28G8MJK |
More data for this Ligand-Target Pair | |