BDBM50275994 (S)-2-cyano-N-(7-oxo-1-(5-phenyl-1H-imidazol-2-yl)octyl)benzenesulfonamide::CHEMBL513756

SMILES: CC(=O)CCCCC[C@H](NS(=O)(=O)c1ccccc1C#N)c1nc(c[nH]1)-c1ccccc1

InChI Key: InChIKey=MQGKODIYTBEYCZ-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50275994 ((S)-2-cyano-N-(7-oxo-1-(5-phenyl-1H-imidazol-2-yl)...) Show SMILES CC(=O)CCCCC[C@H](NS(=O)(=O)c1ccccc1C#N)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C24H26N4O3S/c1-18(29)10-4-2-7-14-21(24-26-17-22(27-24)19-11-5-3-6-12-19)28-32(30,31)23-15-9-8-13-20(23)16-25/h3,5-6,8-9,11-13,15,17,21,28H,2,4,7,10,14H2,1H3,(H,26,27)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminally flag tagged HDAC1				Bioorg Med Chem Lett 18: 5528-32 (2008) Article DOI: 10.1016/j.bmcl.2008.09.003 BindingDB Entry DOI: 10.7270/Q24T6K81
					More data for this Ligand-Target Pair