BDBM50275997 (S)-3-fluoro-4-nitro-N-(7-oxo-1-(5-phenyl-1H-imidazol-2-yl)octyl)benzenesulfonamide::CHEMBL511270

SMILES: CC(=O)CCCCC[C@H](NS(=O)(=O)c1ccc(c(F)c1)[N+]([O-])=O)c1nc(c[nH]1)-c1ccccc1

InChI Key: InChIKey=JAAMXBCUFMLBAV-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50275997 ((S)-3-fluoro-4-nitro-N-(7-oxo-1-(5-phenyl-1H-imida...) Show SMILES CC(=O)CCCCC[C@H](NS(=O)(=O)c1ccc(c(F)c1)[N+]([O-])=O)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C23H25FN4O5S/c1-16(29)8-4-2-7-11-20(23-25-15-21(26-23)17-9-5-3-6-10-17)27-34(32,33)18-12-13-22(28(30)31)19(24)14-18/h3,5-6,9-10,12-15,20,27H,2,4,7-8,11H2,1H3,(H,25,26)/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminally flag tagged HDAC1				Bioorg Med Chem Lett 18: 5528-32 (2008) Article DOI: 10.1016/j.bmcl.2008.09.003 BindingDB Entry DOI: 10.7270/Q24T6K81
					More data for this Ligand-Target Pair