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SMILES: Cc1cccc(C)c1C(=O)N1CCC(CC1)N1CCC(CNC(=O)C2CC2)(Cc2ccccc2)CC1

InChI Key: InChIKey=JVLHJCASAXPVIS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276217   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50276217
PNG
(CHEMBL471403 | N-((4-benzyl-1'-(2,6-dimethylbenzoy...)
Show SMILES Cc1cccc(C)c1C(=O)N1CCC(CC1)N1CCC(CNC(=O)C2CC2)(Cc2ccccc2)CC1
Show InChI InChI=1S/C31H41N3O2/c1-23-7-6-8-24(2)28(23)30(36)34-17-13-27(14-18-34)33-19-15-31(16-20-33,21-25-9-4-3-5-10-25)22-32-29(35)26-11-12-26/h3-10,26-27H,11-22H2,1-2H3,(H,32,35)
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Similars
Article
PubMed
n/an/a 145n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...

Bioorg Med Chem Lett 19: 1084-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.012
BindingDB Entry DOI: 10.7270/Q2W095SG
More data for this
Ligand-Target Pair