BDBM50276484 1-(2,6-diisopropylphenyl)-3-((1-(2-methoxyphenyl)-4-(3-methoxyphenyl)piperidin-4-yl)methyl)urea::CHEMBL510453

SMILES: COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC

InChI Key: InChIKey=ISXLCONDKDAKDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276484 (1-(2,6-diisopropylphenyl)-3-((1-(2-methoxyphenyl)-...) Show SMILES COc1cccc(c1)C1(CNC(=O)Nc2c(cccc2C(C)C)C(C)C)CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C33H43N3O3/c1-23(2)27-13-10-14-28(24(3)4)31(27)35-32(37)34-22-33(25-11-9-12-26(21-25)38-5)17-19-36(20-18-33)29-15-7-8-16-30(29)39-6/h7-16,21,23-24H,17-20,22H2,1-6H3,(H2,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair