BDBM50276493 1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxyphenyl)-4-(3-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)urea::CHEMBL453491

SMILES: COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=KYBJAOXSEYKAOR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50276493 (1-(4-amino-2,6-diisopropylphenyl)-3-((1-(2-methoxy...) Show SMILES COc1ccccc1N1CCC(CNC(=O)Nc2c(cc(N)cc2C(C)C)C(C)C)(CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C33H41F3N4O2/c1-21(2)26-18-25(37)19-27(22(3)4)30(26)39-31(41)38-20-32(23-9-8-10-24(17-23)33(34,35)36)13-15-40(16-14-32)28-11-6-7-12-29(28)42-5/h6-12,17-19,21-22H,13-16,20,37H2,1-5H3,(H2,38,39,41)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of ACAT in human HepG2 cells				Bioorg Med Chem Lett 19: 1062-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.020 BindingDB Entry DOI: 10.7270/Q2R78F3M
					More data for this Ligand-Target Pair