null

SMILES: COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=CUZDBNKFSQWNKG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50276498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50276498 ((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H30Cl2N2O4/c1-27(2)20-9-7-15-13-21(31-4)22(32-5)14-17(15)23(20)28(10-11-30-3)24(29)16-6-8-18(25)19(26)12-16/h6,8,12-14,20,23H,7,9-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Displacement of [125I]deltorphin 2 from human cloned delta opioid receptor				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50276498 ((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H30Cl2N2O4/c1-27(2)20-9-7-15-13-21(31-4)22(32-5)14-17(15)23(20)28(10-11-30-3)24(29)16-6-8-18(25)19(26)12-16/h6,8,12-14,20,23H,7,9-11H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>9.00E+4	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50276498 ((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H30Cl2N2O4/c1-27(2)20-9-7-15-13-21(31-4)22(32-5)14-17(15)23(20)28(10-11-30-3)24(29)16-6-8-18(25)19(26)12-16/h6,8,12-14,20,23H,7,9-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Displacement of [125I]U69593 from human cloned kappa opioid receptor				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50276498 ((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...) Show SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H30Cl2N2O4/c1-27(2)20-9-7-15-13-21(31-4)22(32-5)14-17(15)23(20)28(10-11-30-3)24(29)16-6-8-18(25)19(26)12-16/h6,8,12-14,20,23H,7,9-11H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Displacement of [125I]FK33824 from human cloned mu opioid receptor				Bioorg Med Chem Lett 19: 1228-32 (2009) Article DOI: 10.1016/j.bmcl.2008.12.095 BindingDB Entry DOI: 10.7270/Q2GT5N2W
					More data for this Ligand-Target Pair