BDBM50276573 4-chloro-6-(5-(3,4-dimethoxyphenyl)-1,2,3-thiadiazol-4-yl)benzene-1,3-diol::CHEMBL515048

SMILES: COc1ccc(cc1OC)-c1snnc1-c1cc(Cl)c(O)cc1O

InChI Key: InChIKey=UTWGFIMJBOZKAO-UHFFFAOYSA-N

Data: 1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50276573 (4-chloro-6-(5-(3,4-dimethoxyphenyl)-1,2,3-thiadiaz...) Show SMILES COc1ccc(cc1OC)-c1snnc1-c1cc(Cl)c(O)cc1O Show InChI InChI=1S/C16H13ClN2O4S/c1-22-13-4-3-8(5-14(13)23-2)16-15(18-19-24-16)9-6-10(17)12(21)7-11(9)20/h3-7,20-21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a
Fermentas UAB Curated by ChEMBL					Assay Description Binding affinity to human full length Histidine6-tagged Hsp90alpha expressed in Escherichia coli BL21 DE3 by ITC				Bioorg Med Chem Lett 19: 1089-92 (2009) Article DOI: 10.1016/j.bmcl.2009.01.003 BindingDB Entry DOI: 10.7270/Q27944KP
					More data for this Ligand-Target Pair				3D Structure (crystal)