null

SMILES: C(Cc1c[nH]c2ccccc12)N1CCCC(C1)c1ccnc(NCC2CC2)n1

InChI Key: InChIKey=DRZMEJAAZMHAGA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50277130 ((+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)...) Show SMILES C(Cc1c[nH]c2ccccc12)N1CCCC(C1)c1ccnc(NCC2CC2)n1 Show InChI InChI=1S/C23H29N5/c1-2-6-22-20(5-1)18(15-25-22)10-13-28-12-3-4-19(16-28)21-9-11-24-23(27-21)26-14-17-7-8-17/h1-2,5-6,9,11,15,17,19,25H,3-4,7-8,10,12-14,16H2,(H,24,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor				Bioorg Med Chem Lett 19: 1159-63 (2009) Article DOI: 10.1016/j.bmcl.2008.12.087 BindingDB Entry DOI: 10.7270/Q29886VW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50277130 ((+/-)-4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)...) Show SMILES C(Cc1c[nH]c2ccccc12)N1CCCC(C1)c1ccnc(NCC2CC2)n1 Show InChI InChI=1S/C23H29N5/c1-2-6-22-20(5-1)18(15-25-22)10-13-28-12-3-4-19(16-28)21-9-11-24-23(27-21)26-14-17-7-8-17/h1-2,5-6,9,11,15,17,19,25H,3-4,7-8,10,12-14,16H2,(H,24,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	147	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5HT1A receptor expressed in CHO cells by FLIPR				Bioorg Med Chem Lett 19: 1159-63 (2009) Article DOI: 10.1016/j.bmcl.2008.12.087 BindingDB Entry DOI: 10.7270/Q29886VW
					More data for this Ligand-Target Pair