BDBM50277194 4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfonyl)morpholine::CHEMBL474897
SMILES: Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC(C)(C)C)cs1
InChI Key: InChIKey=RJAYJQVMQVZMSL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50277194 (4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry | Bioorg Med Chem Lett 19: 309-13 (2008) Article DOI: 10.1016/j.bmcl.2008.11.091 BindingDB Entry DOI: 10.7270/Q2G73DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50277194 (4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Displacement of [3H]CP 55940 from human CB2 receptor in cell free system | Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50277194 (4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from human cloned CB1 receptor by scintillation spectrometry | Bioorg Med Chem Lett 19: 309-13 (2008) Article DOI: 10.1016/j.bmcl.2008.11.091 BindingDB Entry DOI: 10.7270/Q2G73DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50277194 (4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Displacement of [3H]CP 55940 from human CB1 receptor in cell free system | Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50277194 (4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS binding | Bioorg Med Chem Lett 19: 309-13 (2008) Article DOI: 10.1016/j.bmcl.2008.11.091 BindingDB Entry DOI: 10.7270/Q2G73DK3 | |||||||||||
More data for this Ligand-Target Pair |