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BDBM50277224 4-(5-(2-(cyclohexylmethyl)-2H-tetrazol-5-yl)-2-methylphenylsulfonyl)morpholine::CHEMBL475100

SMILES: Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnn(CC2CCCCC2)n1

InChI Key: InChIKey=LCMILIMARCFGTR-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277224   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277224
PNG
(4-(5-(2-(cyclohexylmethyl)-2H-tetrazol-5-yl)-2-met...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnn(CC2CCCCC2)n1
Show InChI InChI=1S/C19H27N5O3S/c1-15-7-8-17(13-18(15)28(25,26)23-9-11-27-12-10-23)19-20-22-24(21-19)14-16-5-3-2-4-6-16/h7-8,13,16H,2-6,9-12,14H2,1H3
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PC cid
PC sid
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82n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50277224
PNG
(4-(5-(2-(cyclohexylmethyl)-2H-tetrazol-5-yl)-2-met...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnn(CC2CCCCC2)n1
Show InChI InChI=1S/C19H27N5O3S/c1-15-7-8-17(13-18(15)28(25,26)23-9-11-27-12-10-23)19-20-22-24(21-19)14-16-5-3-2-4-6-16/h7-8,13,16H,2-6,9-12,14H2,1H3
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560n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB1 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277224
PNG
(4-(5-(2-(cyclohexylmethyl)-2H-tetrazol-5-yl)-2-met...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnn(CC2CCCCC2)n1
Show InChI InChI=1S/C19H27N5O3S/c1-15-7-8-17(13-18(15)28(25,26)23-9-11-27-12-10-23)19-20-22-24(21-19)14-16-5-3-2-4-6-16/h7-8,13,16H,2-6,9-12,14H2,1H3
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n/an/an/an/a 78n/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS binding


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair