null

SMILES: COCCNc1nccc(n1)C1CCCN(CCc2c[nH]c3ccccc23)C1

InChI Key: InChIKey=NYTBSMRRGSUXPY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50277252 (4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(2-...) Show SMILES COCCNc1nccc(n1)C1CCCN(CCc2c[nH]c3ccccc23)C1 Show InChI InChI=1S/C22H29N5O/c1-28-14-11-24-22-23-10-8-20(26-22)18-5-4-12-27(16-18)13-9-17-15-25-21-7-3-2-6-19(17)21/h2-3,6-8,10,15,18,25H,4-5,9,11-14,16H2,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor				Bioorg Med Chem Lett 19: 1159-63 (2009) Article DOI: 10.1016/j.bmcl.2008.12.087 BindingDB Entry DOI: 10.7270/Q29886VW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50277252 (4-(1-(2-(1H-indol-3-yl)ethyl)piperidin-3-yl)-N-(2-...) Show SMILES COCCNc1nccc(n1)C1CCCN(CCc2c[nH]c3ccccc23)C1 Show InChI InChI=1S/C22H29N5O/c1-28-14-11-24-22-23-10-8-20(26-22)18-5-4-12-27(16-18)13-9-17-15-25-21-7-3-2-6-19(17)21/h2-3,6-8,10,15,18,25H,4-5,9,11-14,16H2,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40.7	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5HT1A receptor expressed in CHO cells by FLIPR				Bioorg Med Chem Lett 19: 1159-63 (2009) Article DOI: 10.1016/j.bmcl.2008.12.087 BindingDB Entry DOI: 10.7270/Q29886VW
					More data for this Ligand-Target Pair