BDBM50277309 3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholinosulfonyl)phenyl)-2-(trifluoromethyl)propanamide::CHEMBL511150

SMILES: Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1

InChI Key: InChIKey=KYLMGDPJMOYDEV-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50277309 (3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...) Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H18F6N2O4S/c1-10-3-4-11(9-12(10)29(26,27)24-5-7-28-8-6-24)23-13(25)14(2,15(17,18)19)16(20,21)22/h3-4,9H,5-8H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry				Bioorg Med Chem Lett 19: 309-13 (2008) Article DOI: 10.1016/j.bmcl.2008.11.091 BindingDB Entry DOI: 10.7270/Q2G73DK3
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50277309 (3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...) Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H18F6N2O4S/c1-10-3-4-11(9-12(10)29(26,27)24-5-7-28-8-6-24)23-13(25)14(2,15(17,18)19)16(20,21)22/h3-4,9H,5-8H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]CP 55940 from human CB2 receptor in cell free system				Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50277309 (3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...) Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H18F6N2O4S/c1-10-3-4-11(9-12(10)29(26,27)24-5-7-28-8-6-24)23-13(25)14(2,15(17,18)19)16(20,21)22/h3-4,9H,5-8H2,1-2H3,(H,23,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human cloned CB1 receptor by scintillation spectrometry				Bioorg Med Chem Lett 19: 309-13 (2008) Article DOI: 10.1016/j.bmcl.2008.11.091 BindingDB Entry DOI: 10.7270/Q2G73DK3
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50277309 (3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...) Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H18F6N2O4S/c1-10-3-4-11(9-12(10)29(26,27)24-5-7-28-8-6-24)23-13(25)14(2,15(17,18)19)16(20,21)22/h3-4,9H,5-8H2,1-2H3,(H,23,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Displacement of [3H]CP 55940 from human CB1 receptor in cell free system				Eur J Med Chem 46: 547-55 (2011) Article DOI: 10.1016/j.ejmech.2010.11.034 BindingDB Entry DOI: 10.7270/Q2CF9QCJ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50277309 (3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...) Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C16H18F6N2O4S/c1-10-3-4-11(9-12(10)29(26,27)24-5-7-28-8-6-24)23-13(25)14(2,15(17,18)19)16(20,21)22/h3-4,9H,5-8H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Agonist activity at human cloned CB2 receptor assessed as stimulation of [35S]GTPgammaS binding				Bioorg Med Chem Lett 19: 309-13 (2008) Article DOI: 10.1016/j.bmcl.2008.11.091 BindingDB Entry DOI: 10.7270/Q2G73DK3
					More data for this Ligand-Target Pair