BDBM50277675 2-(3-(6-hydroxy-1-methyl-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)propanamido)benzoic acid::CHEMBL483996

SMILES: Cn1nc(CCC(=O)Nc2ccccc2C(O)=O)c2Cc3cc(O)ccc3-c12

InChI Key: InChIKey=KAJYWMWSDDQACU-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277675 (2-(3-(6-hydroxy-1-methyl-1,4-dihydroindeno[1,2-c]p...) Show SMILES Cn1nc(CCC(=O)Nc2ccccc2C(O)=O)c2Cc3cc(O)ccc3-c12 Show InChI InChI=1S/C21H19N3O4/c1-24-20-14-7-6-13(25)10-12(14)11-16(20)18(23-24)8-9-19(26)22-17-5-3-2-4-15(17)21(27)28/h2-7,10,25H,8-9,11H2,1H3,(H,22,26)(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assay				J Med Chem 52: 2587-602 (2009) Article DOI: 10.1021/jm900151e BindingDB Entry DOI: 10.7270/Q2RJ4JDG
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277675 (2-(3-(6-hydroxy-1-methyl-1,4-dihydroindeno[1,2-c]p...) Show SMILES Cn1nc(CCC(=O)Nc2ccccc2C(O)=O)c2Cc3cc(O)ccc3-c12 Show InChI InChI=1S/C21H19N3O4/c1-24-20-14-7-6-13(25)10-12(14)11-16(20)18(23-24)8-9-19(26)22-17-5-3-2-4-15(17)21(27)28/h2-7,10,25H,8-9,11H2,1H3,(H,22,26)(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human GPR109A expressed in CHO cells				J Med Chem 52: 2587-602 (2009) Article DOI: 10.1021/jm900151e BindingDB Entry DOI: 10.7270/Q2RJ4JDG
					More data for this Ligand-Target Pair