BDBM50277789 3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole::CHEMBL520137

SMILES: Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1

InChI Key: InChIKey=HJLIOQAZIYHNGR-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50277789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Mus musculus)	BDBM50277789 (3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...) Show SMILES Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9F3N6/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13-19-21-22-20-13/h3-5H,1-2H2,(H,17,18)(H,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from mouse GPR10a receptor				Bioorg Med Chem Lett 20: 4472-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.041 BindingDB Entry DOI: 10.7270/Q2B858B5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277789 (3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...) Show SMILES Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9F3N6/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13-19-21-22-20-13/h3-5H,1-2H2,(H,17,18)(H,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from human GPR10a receptor				Bioorg Med Chem Lett 20: 4472-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.041 BindingDB Entry DOI: 10.7270/Q2B858B5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Mus musculus)	BDBM50277789 (3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...) Show SMILES Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9F3N6/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13-19-21-22-20-13/h3-5H,1-2H2,(H,17,18)(H,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from mouse GPR109a receptor				Bioorg Med Chem Lett 19: 2121-4 (2009) Article DOI: 10.1016/j.bmcl.2009.03.014 BindingDB Entry DOI: 10.7270/Q2G161RV
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277789 (3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...) Show SMILES Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9F3N6/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13-19-21-22-20-13/h3-5H,1-2H2,(H,17,18)(H,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from human GPR109a receptor				Bioorg Med Chem Lett 19: 2121-4 (2009) Article DOI: 10.1016/j.bmcl.2009.03.014 BindingDB Entry DOI: 10.7270/Q2G161RV
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Mus musculus)	BDBM50277789 (3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...) Show SMILES Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9F3N6/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13-19-21-22-20-13/h3-5H,1-2H2,(H,17,18)(H,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from mouse GPR109a receptor				Bioorg Med Chem Lett 19: 2121-4 (2009) Article DOI: 10.1016/j.bmcl.2009.03.014 BindingDB Entry DOI: 10.7270/Q2G161RV
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50277789 (3-(1H-tetrazol-5-yl)-5-(2,3,5-trifluorophenyl)-1,4...) Show SMILES Fc1cc(F)c(F)c(c1)C1Cc2[nH]nc(c2C1)-c1nnn[nH]1 Show InChI InChI=1S/C13H9F3N6/c14-6-3-7(11(16)9(15)4-6)5-1-8-10(2-5)17-18-12(8)13-19-21-22-20-13/h3-5H,1-2H2,(H,17,18)(H,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nicotinic acid from human GPR109a receptor				Bioorg Med Chem Lett 19: 2121-4 (2009) Article DOI: 10.1016/j.bmcl.2009.03.014 BindingDB Entry DOI: 10.7270/Q2G161RV
					More data for this Ligand-Target Pair