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SMILES: CN1[C@H]([C@H](C(O)=O)c2ccccc2C1=O)c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=JDYIMYZYEPQLHV-RTWAWAEBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277813   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50277813
PNG
((3R,4R)-2-methyl-1-oxo-3-(4-phenoxyphenyl)-1,2,3,4...)
Show SMILES CN1[C@H]([C@H](C(O)=O)c2ccccc2C1=O)c1ccc(Oc2ccccc2)cc1 |r|
Show InChI InChI=1S/C23H19NO4/c1-24-21(20(23(26)27)18-9-5-6-10-19(18)22(24)25)15-11-13-17(14-12-15)28-16-7-3-2-4-8-16/h2-14,20-21H,1H3,(H,26,27)/t20-,21+/m1/s1
PDB

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UniChem

Similars
Article
PubMed
n/an/a 156n/an/an/an/an/an/a



Pfizer Global R&D

Curated by ChEMBL


Assay Description
Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assay

Bioorg Med Chem Lett 19: 2400-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.082
BindingDB Entry DOI: 10.7270/Q23N238P
More data for this
Ligand-Target Pair