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BDBM50277908 CHEMBL518996::N-(1-methylpiperidin-4-yl)-4-(3-(6-methylpyridin-3-yl)-1H-pyrazol-4-yl)pyrimidin-2-amine

SMILES: CN1CCC(CC1)Nc1nccc(n1)-c1c[nH]nc1-c1ccc(C)nc1

InChI Key: InChIKey=OCCFGHAWQLCASO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277908   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
c-Jun N-terminal kinase, JNK


(Homo sapiens (Human))
BDBM50277908
PNG
(CHEMBL518996 | N-(1-methylpiperidin-4-yl)-4-(3-(6-...)
Show SMILES CN1CCC(CC1)Nc1nccc(n1)-c1c[nH]nc1-c1ccc(C)nc1
Show InChI InChI=1S/C19H23N7/c1-13-3-4-14(11-21-13)18-16(12-22-25-18)17-5-8-20-19(24-17)23-15-6-9-26(2)10-7-15/h3-5,8,11-12,15H,6-7,9-10H2,1-2H3,(H,22,25)(H,20,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
162n/an/an/an/an/an/an/an/a



Pfizer Global R&D

Curated by ChEMBL


Assay Description
Inhibition of JNK1


Bioorg Med Chem Lett 19: 2099-102 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.023
BindingDB Entry DOI: 10.7270/Q26H4H9D
More data for this
Ligand-Target Pair