BDBM50277938 (+/-)-2-(4-(methylsulfonyl)-5-(p-tolylthio)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid::CHEMBL485535
SMILES: Cc1ccc(Sc2c3C(CC(O)=O)CCCn3c3nccc(c23)S(C)(=O)=O)cc1
InChI Key: InChIKey=OOPPXCLFSYMOMD-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid DP receptor (Homo sapiens (Human)) | BDBM50277938 ((+/-)-2-(4-(methylsulfonyl)-5-(p-tolylthio)-6,7,8,...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Displacement of radioligand from human recombinant DP1 receptor expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 2125-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.010 BindingDB Entry DOI: 10.7270/Q2W9593R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50277938 ((+/-)-2-(4-(methylsulfonyl)-5-(p-tolylthio)-6,7,8,...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 172 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Displacement of radioligand from human recombinant TP receptor expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 19: 2125-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.010 BindingDB Entry DOI: 10.7270/Q2W9593R | |||||||||||
More data for this Ligand-Target Pair |