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SMILES: CN(C)c1cc2c(ncnc2cn1)N(C)C1Cc2ccccc2C1

InChI Key: InChIKey=NNMBCEAGVMXJQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278110   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(RAT)		BDBM50278110
PNG
(CHEMBL511838 | N4-(2,3-dihydro-1H-inden-2-yl)-N4,N...)
Show SMILES CN(C)c1cc2c(ncnc2cn1)N(C)C1Cc2ccccc2C1
Show InChI InChI=1S/C19H21N5/c1-23(2)18-10-16-17(11-20-18)21-12-22-19(16)24(3)15-8-13-6-4-5-7-14(13)9-15/h4-7,10-12,15H,8-9H2,1-3H3
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PC cid
PC sid
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Similars
Article
PubMed
 300n/an/an/an/an/an/an/an/a



Medical Research Council Technology

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...

Bioorg Med Chem Lett 19: 2190-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.106
BindingDB Entry DOI: 10.7270/Q2057FSP
More data for this
Ligand-Target Pair