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SMILES: COc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1

InChI Key: InChIKey=LIFCGRIUBCJQDT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278113   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(RAT)		BDBM50278113
PNG
(CHEMBL513761 | N-(2,3-dihydro-1H-inden-2-yl)-6-met...)
Show SMILES COc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1
Show InChI InChI=1S/C17H16N4O/c1-22-16-8-14-15(9-18-16)19-10-20-17(14)21-13-6-11-4-2-3-5-12(11)7-13/h2-5,8-10,13H,6-7H2,1H3,(H,19,20,21)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 115n/an/an/an/an/an/an/an/a



Medical Research Council Technology

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...

Bioorg Med Chem Lett 19: 2190-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.106
BindingDB Entry DOI: 10.7270/Q2057FSP
More data for this
Ligand-Target Pair