BDBM50278114 CHEMBL513012::N-cyclohexylquinazolin-4-amine

SMILES: C1CCC(CC1)Nc1ncnc2ccccc12

InChI Key: InChIKey=CIFOBGKTSPXVQX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50278114 (CHEMBL513012 | N-cyclohexylquinazolin-4-amine) Show SMILES C1CCC(CC1)Nc1ncnc2ccccc12 Show InChI InChI=1S/C14H17N3/c1-2-6-11(7-3-1)17-14-12-8-4-5-9-13(12)15-10-16-14/h4-5,8-11H,1-3,6-7H2,(H,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair