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SMILES: NCCCNc1cc2c(NC3CCCCC3)ncnc2cn1

InChI Key: InChIKey=YYBIHKMINYNWQT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278360   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(RAT)		BDBM50278360
PNG
(CHEMBL471434 | N6-(3-aminopropyl)-N4-cyclohexylpyr...)
Show SMILES NCCCNc1cc2c(NC3CCCCC3)ncnc2cn1
Show InChI InChI=1S/C16H24N6/c17-7-4-8-18-15-9-13-14(10-19-15)20-11-21-16(13)22-12-5-2-1-3-6-12/h9-12H,1-8,17H2,(H,18,19)(H,20,21,22)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 200n/an/an/an/an/an/an/an/a



Medical Research Council Technology

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...

Bioorg Med Chem Lett 19: 2190-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.106
BindingDB Entry DOI: 10.7270/Q2057FSP
More data for this
Ligand-Target Pair