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SMILES: Cc1cccc(C)c1Oc1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=WGPKLDKIJUOVQB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50278401 (4-(2,6-dimethylphenoxy)-2-(trifluoromethyl)benzoni...) Show SMILES Cc1cccc(C)c1Oc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C16H12F3NO/c1-10-4-3-5-11(2)15(10)21-13-7-6-12(9-20)14(8-13)16(17,18)19/h3-8H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	681	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced response				Bioorg Med Chem Lett 19: 2176-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.104 BindingDB Entry DOI: 10.7270/Q27P8Z8W
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50278401 (4-(2,6-dimethylphenoxy)-2-(trifluoromethyl)benzoni...) Show SMILES Cc1cccc(C)c1Oc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C16H12F3NO/c1-10-4-3-5-11(2)15(10)21-13-7-6-12(9-20)14(8-13)16(17,18)19/h3-8H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell system				Bioorg Med Chem Lett 19: 2176-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.104 BindingDB Entry DOI: 10.7270/Q27P8Z8W
					More data for this Ligand-Target Pair