BDBM50278446 (R)-3-fluoro-1-(4-(3-(pyrrolidin-1-yl)propoxy)benzyl)pyrrolidine::CHEMBL452877

SMILES: F[C@@H]1CCN(Cc2ccc(OCCCN3CCCC3)cc2)C1

InChI Key: InChIKey=KFCAEZIVWPWJSG-QGZVFWFLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50278446 ((R)-3-fluoro-1-(4-(3-(pyrrolidin-1-yl)propoxy)benz...) Show SMILES F[C@@H]1CCN(Cc2ccc(OCCCN3CCCC3)cc2)C1 |r| Show InChI InChI=1S/C18H27FN2O/c19-17-8-12-21(15-17)14-16-4-6-18(7-5-16)22-13-3-11-20-9-1-2-10-20/h4-7,17H,1-3,8-15H2/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cells				Bioorg Med Chem Lett 19: 2172-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.110 BindingDB Entry DOI: 10.7270/Q2H41RBM
					More data for this Ligand-Target Pair