BDBM50278467 CHEMBL511473::ethyl 4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzyl(ethyl)phosphinate

SMILES: CCOP(=O)(CC)Cc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1

InChI Key: InChIKey=KFGDGDXWTSPQRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50278467 (CHEMBL511473 | ethyl 4-(2-amino-5-(thiophen-2-yl)p...) Show SMILES CCOP(=O)(CC)Cc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C22H25N2O3PS/c1-3-27-28(26,4-2)15-16-7-9-17(10-8-16)22(25)24-20-14-18(11-12-19(20)23)21-6-5-13-29-21/h5-14H,3-4,15,23H2,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 19: 2053-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.009 BindingDB Entry DOI: 10.7270/Q2QV3MDQ
					More data for this Ligand-Target Pair