BDBM50278474 3-Benzyl-8-bromo-5-methoxychromen-2-one::CHEMBL470019

SMILES: COc1ccc(Br)c2oc(=O)c(Cc3ccccc3)cc12

InChI Key: InChIKey=OPRKTEJKHGVKBY-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50278474 (3-Benzyl-8-bromo-5-methoxychromen-2-one | CHEMBL47...) Show SMILES COc1ccc(Br)c2oc(=O)c(Cc3ccccc3)cc12 Show InChI InChI=1S/C17H13BrO3/c1-20-15-8-7-14(18)16-13(15)10-12(17(19)21-16)9-11-5-3-2-4-6-11/h2-8,10H,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in HEK293 cells				Bioorg Med Chem 17: 2842-51 (2009) Article DOI: 10.1016/j.bmc.2009.02.027 BindingDB Entry DOI: 10.7270/Q23R0TSC
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50278474 (3-Benzyl-8-bromo-5-methoxychromen-2-one | CHEMBL47...) Show SMILES COc1ccc(Br)c2oc(=O)c(Cc3ccccc3)cc12 Show InChI InChI=1S/C17H13BrO3/c1-20-15-8-7-14(18)16-13(15)10-12(17(19)21-16)9-11-5-3-2-4-6-11/h2-8,10H,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from cannabinoid CB1 receptor in rat brain cortical membrane				Bioorg Med Chem 17: 2842-51 (2009) Article DOI: 10.1016/j.bmc.2009.02.027 BindingDB Entry DOI: 10.7270/Q23R0TSC
					More data for this Ligand-Target Pair
G-protein coupled receptor 55 (Homo sapiens (Human))	BDBM50278474 (3-Benzyl-8-bromo-5-methoxychromen-2-one | CHEMBL47...) Show SMILES COc1ccc(Br)c2oc(=O)c(Cc3ccccc3)cc12 Show InChI InChI=1S/C17H13BrO3/c1-20-15-8-7-14(18)16-13(15)10-12(17(19)21-16)9-11-5-3-2-4-6-11/h2-8,10H,9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Antagonist activity at human GPR55 transfected in CHO cells assessed as inhibition of LPI-induced beta-arrestin recruitment incubated 60 mins prior t...				J Med Chem 56: 4798-810 (2013) Article DOI: 10.1021/jm4005175 BindingDB Entry DOI: 10.7270/Q2GM88QX
					More data for this Ligand-Target Pair