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BDBM50278534 CHEMBL512672::N-(2-amino-1-phenylethyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES: NCC(NC(=O)c1cc(cs1)-c1ccnc2[nH]ccc12)c1ccccc1

InChI Key: InChIKey=FRSCXNVIGBMZPG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50278534
PNG
(CHEMBL512672 | N-(2-amino-1-phenylethyl)-4-(1H-pyr...)
Show SMILES NCC(NC(=O)c1cc(cs1)-c1ccnc2[nH]ccc12)c1ccccc1
Show InChI InChI=1S/C20H18N4OS/c21-11-17(13-4-2-1-3-5-13)24-20(25)18-10-14(12-26-18)15-6-8-22-19-16(15)7-9-23-19/h1-10,12,17H,11,21H2,(H,22,23)(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of AKT1


Bioorg Med Chem Lett 19: 2244-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.094
BindingDB Entry DOI: 10.7270/Q24X57PX
More data for this
Ligand-Target Pair