BDBM50278566 CHEMBL469560::N1-((5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophen-2-yl)methyl)-1-phenylethane-1,2-diamine

SMILES: NCC(NCc1ccc(s1)-c1ccnc2[nH]ccc12)c1ccccc1

InChI Key: InChIKey=ZSJZLUDDBSGIPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50278566 (CHEMBL469560 | N1-((5-(1H-pyrrolo[2,3-b]pyridin-4-...) Show SMILES NCC(NCc1ccc(s1)-c1ccnc2[nH]ccc12)c1ccccc1 Show InChI InChI=1S/C20H20N4S/c21-12-18(14-4-2-1-3-5-14)24-13-15-6-7-19(25-15)16-8-10-22-20-17(16)9-11-23-20/h1-11,18,24H,12-13,21H2,(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair