BDBM50278568 CHEMBL512480::N-(5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophen-2-yl)-3-amino-2-phenylpropanamide

SMILES: NCC(C(=O)Nc1ccc(s1)-c1ccnc2[nH]ccc12)c1ccccc1

InChI Key: InChIKey=SZPYEVURGKSXEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase AKT1 (Homo sapiens (Human))	BDBM50278568 (CHEMBL512480 | N-(5-(1H-pyrrolo[2,3-b]pyridin-4-yl...) Show SMILES NCC(C(=O)Nc1ccc(s1)-c1ccnc2[nH]ccc12)c1ccccc1 Show InChI InChI=1S/C20H18N4OS/c21-12-16(13-4-2-1-3-5-13)20(25)24-18-7-6-17(26-18)14-8-10-22-19-15(14)9-11-23-19/h1-11,16H,12,21H2,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair