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BDBM50278569 3-amino-N-(4-bromo-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophen-2-yl)-2-phenylpropanamide::CHEMBL472291

SMILES: NCC(C(=O)Nc1cc(Br)c(s1)-c1ccnc2[nH]ccc12)c1ccccc1

InChI Key: InChIKey=FUHANCRIAJEKGA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278569   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50278569
PNG
(3-amino-N-(4-bromo-5-(1H-pyrrolo[2,3-b]pyridin-4-y...)
Show SMILES NCC(C(=O)Nc1cc(Br)c(s1)-c1ccnc2[nH]ccc12)c1ccccc1
Show InChI InChI=1S/C20H17BrN4OS/c21-16-10-17(25-20(26)15(11-22)12-4-2-1-3-5-12)27-18(16)13-6-8-23-19-14(13)7-9-24-19/h1-10,15H,11,22H2,(H,23,24)(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of AKT1


Bioorg Med Chem Lett 19: 2244-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.094
BindingDB Entry DOI: 10.7270/Q24X57PX
More data for this
Ligand-Target Pair