BDBM50278605 CHEMBL512858::N-(2-amino-1-phenylethyl)-4-cyclopropyl-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES: NCC(NC(=O)c1cc(C2CC2)c(s1)-c1ccnc2[nH]ccc12)c1ccccc1

InChI Key: InChIKey=ZXAIWDLCJKVDIG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50278605 (CHEMBL512858 | N-(2-amino-1-phenylethyl)-4-cyclopr...) Show SMILES NCC(NC(=O)c1cc(C2CC2)c(s1)-c1ccnc2[nH]ccc12)c1ccccc1 Show InChI InChI=1S/C23H22N4OS/c24-13-19(15-4-2-1-3-5-15)27-23(28)20-12-18(14-6-7-14)21(29-20)16-8-10-25-22-17(16)9-11-26-22/h1-5,8-12,14,19H,6-7,13,24H2,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair