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BDBM50278606 CHEMBL470200::N-(2-amino-1-phenylethyl)-4-phenyl-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES: NCC(NC(=O)c1cc(c(s1)-c1ccnc2[nH]ccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=NOROMZLDWXCWKI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50278606
PNG
(CHEMBL470200 | N-(2-amino-1-phenylethyl)-4-phenyl-...)
Show SMILES NCC(NC(=O)c1cc(c(s1)-c1ccnc2[nH]ccc12)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H22N4OS/c27-16-22(18-9-5-2-6-10-18)30-26(31)23-15-21(17-7-3-1-4-8-17)24(32-23)19-11-13-28-25-20(19)12-14-29-25/h1-15,22H,16,27H2,(H,28,29)(H,30,31)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of AKT1


Bioorg Med Chem Lett 19: 2244-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.094
BindingDB Entry DOI: 10.7270/Q24X57PX
More data for this
Ligand-Target Pair