BDBM50278606 CHEMBL470200::N-(2-amino-1-phenylethyl)-4-phenyl-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES: NCC(NC(=O)c1cc(c(s1)-c1ccnc2[nH]ccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=NOROMZLDWXCWKI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50278606 (CHEMBL470200 | N-(2-amino-1-phenylethyl)-4-phenyl-...) Show SMILES NCC(NC(=O)c1cc(c(s1)-c1ccnc2[nH]ccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H22N4OS/c27-16-22(18-9-5-2-6-10-18)30-26(31)23-15-21(17-7-3-1-4-8-17)24(32-23)19-11-13-28-25-20(19)12-14-29-25/h1-15,22H,16,27H2,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair