BDBM50278644 CHEMBL469357::N-(2-amino-1-phenylethyl)-4-(pyridin-3-yl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES: NCC(NC(=O)c1cc(c(s1)-c1ccnc2[nH]ccc12)-c1cccnc1)c1ccccc1

InChI Key: InChIKey=UBUQHYCGGSQUBW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50278644 (CHEMBL469357 | N-(2-amino-1-phenylethyl)-4-(pyridi...) Show SMILES NCC(NC(=O)c1cc(c(s1)-c1ccnc2[nH]ccc12)-c1cccnc1)c1ccccc1 Show InChI InChI=1S/C25H21N5OS/c26-14-21(16-5-2-1-3-6-16)30-25(31)22-13-20(17-7-4-10-27-15-17)23(32-22)18-8-11-28-24-19(18)9-12-29-24/h1-13,15,21H,14,26H2,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1				Bioorg Med Chem Lett 19: 2244-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.094 BindingDB Entry DOI: 10.7270/Q24X57PX
					More data for this Ligand-Target Pair