BDBM50278840 (R)-tert-butyl 4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)piperidine-1-carboxylate::CHEMBL496863

SMILES: CC(C)(C)OC(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=SMWIXKKUHQMTCS-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50278840 ((R)-tert-butyl 4-(1-amino-2-(2,4,5-trifluorophenyl...) Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C18H25F3N2O2/c1-18(2,3)25-17(24)23-6-4-11(5-7-23)16(22)9-12-8-14(20)15(21)10-13(12)19/h8,10-11,16H,4-7,9,22H2,1-3H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 19: 2220-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.099 BindingDB Entry DOI: 10.7270/Q2RN37QF
					More data for this Ligand-Target Pair