BDBM50278907 CHEMBL497727::cis-2-(6-Phenyl-pyridin-3-yl)-octahydro-pyrrolo[3,4-c]pyrrole Bis-trifluoroacetate

SMILES: C1NC[C@@H]2CN(C[C@H]12)c1ccc(nc1)-c1ccccc1

InChI Key: InChIKey=OREHKCAJBKZGSF-GASCZTMLSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50278907 (CHEMBL497727 | cis-2-(6-Phenyl-pyridin-3-yl)-octah...) Show SMILES C1NC[C@@H]2CN(C[C@H]12)c1ccc(nc1)-c1ccccc1 |r| Show InChI InChI=1S/C17H19N3/c1-2-4-13(5-3-1)17-7-6-16(10-19-17)20-11-14-8-18-9-15(14)12-20/h1-7,10,14-15,18H,8-9,11-12H2/t14-,15+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A585539 from alpha7 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane				J Med Chem 52: 4126-41 (2009) Article DOI: 10.1021/jm900249k BindingDB Entry DOI: 10.7270/Q2GT5P3R
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50278907 (CHEMBL497727 | cis-2-(6-Phenyl-pyridin-3-yl)-octah...) Show SMILES C1NC[C@@H]2CN(C[C@H]12)c1ccc(nc1)-c1ccccc1 |r| Show InChI InChI=1S/C17H19N3/c1-2-4-13(5-3-1)17-7-6-16(10-19-17)20-11-14-8-18-9-15(14)12-20/h1-7,10,14-15,18H,8-9,11-12H2/t14-,15+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane				J Med Chem 52: 4126-41 (2009) Article DOI: 10.1021/jm900249k BindingDB Entry DOI: 10.7270/Q2GT5P3R
					More data for this Ligand-Target Pair