null

SMILES: CN1C[C@H]2CN(C[C@H]2C1)c1ccc(cn1)-c1ccccc1

InChI Key: InChIKey=YKCUHKQRSQKZMT-CALCHBBNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50278933 (CHEMBL496891 | cis-2-Methyl-5-(5-phenyl-pyridin-2-...) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)c1ccc(cn1)-c1ccccc1 |r| Show InChI InChI=1S/C18H21N3/c1-20-10-16-12-21(13-17(16)11-20)18-8-7-15(9-19-18)14-5-3-2-4-6-14/h2-9,16-17H,10-13H2,1H3/t16-,17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]A585539 from alpha7 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane				J Med Chem 52: 4126-41 (2009) Article DOI: 10.1021/jm900249k BindingDB Entry DOI: 10.7270/Q2GT5P3R
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50278933 (CHEMBL496891 | cis-2-Methyl-5-(5-phenyl-pyridin-2-...) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)c1ccc(cn1)-c1ccccc1 |r| Show InChI InChI=1S/C18H21N3/c1-20-10-16-12-21(13-17(16)11-20)18-8-7-15(9-19-18)14-5-3-2-4-6-14/h2-9,16-17H,10-13H2,1H3/t16-,17+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain minus cerebellum membrane				J Med Chem 52: 4126-41 (2009) Article DOI: 10.1021/jm900249k BindingDB Entry DOI: 10.7270/Q2GT5P3R
					More data for this Ligand-Target Pair