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SMILES: Cc1ccc(cc1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12

InChI Key: InChIKey=KCIOJLFKVQHRPU-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279063   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily A member 3


(Homo sapiens (Human))
BDBM50279063
PNG
(5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one | CHEMBL49...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12
Show InChI InChI=1S/C21H17NO3S/c1-15-10-12-16(13-11-15)26(24,25)22-14-21(23)19-8-3-2-6-17(19)18-7-4-5-9-20(18)22/h2-13H,14H2,1H3
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



4SC AG

Curated by ChEMBL


Assay Description
Inhibition of cloned Kv1.3 channel (unknown origin) expressed in mammalian cells by whole cell patch clamp assay


Bioorg Med Chem Lett 19: 2299-304 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.077
BindingDB Entry DOI: 10.7270/Q29K4B38
More data for this
Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM50279063
PNG
(5-tosyl-5H-dibenzo[b,d]azepin-7(6H)-one | CHEMBL49...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12
Show InChI InChI=1S/C21H17NO3S/c1-15-10-12-16(13-11-15)26(24,25)22-14-21(23)19-8-3-2-6-17(19)18-7-4-5-9-20(18)22/h2-13H,14H2,1H3
PDB

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UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



4SC AG

Curated by ChEMBL


Assay Description
Inhibition of human cloned IK1 expressed in african green monkey COS7 cells by whole cell patch clamp assay


Bioorg Med Chem Lett 19: 2299-304 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.077
BindingDB Entry DOI: 10.7270/Q29K4B38
More data for this
Ligand-Target Pair