BDBM50279104 5-(4-methylbenzoyl)-5H-dibenzo[b,d]azepin-7(6H)-one::CHEMBL522408

SMILES: Cc1ccc(cc1)C(=O)N1CC(=O)c2ccccc2-c2ccccc12

InChI Key: InChIKey=FQNVCQZMLKZZBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50279104 (5-(4-methylbenzoyl)-5H-dibenzo[b,d]azepin-7(6H)-on...) Show SMILES Cc1ccc(cc1)C(=O)N1CC(=O)c2ccccc2-c2ccccc12 Show InChI InChI=1S/C22H17NO2/c1-15-10-12-16(13-11-15)22(25)23-14-21(24)19-8-3-2-6-17(19)18-7-4-5-9-20(18)23/h2-13H,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
4SC AG Curated by ChEMBL					Assay Description Inhibition of human cloned IK1 expressed in african green monkey COS7 cells by whole cell patch clamp assay				Bioorg Med Chem Lett 19: 2299-304 (2009) Article DOI: 10.1016/j.bmcl.2009.02.077 BindingDB Entry DOI: 10.7270/Q29K4B38
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50279104 (5-(4-methylbenzoyl)-5H-dibenzo[b,d]azepin-7(6H)-on...) Show SMILES Cc1ccc(cc1)C(=O)N1CC(=O)c2ccccc2-c2ccccc12 Show InChI InChI=1S/C22H17NO2/c1-15-10-12-16(13-11-15)22(25)23-14-21(24)19-8-3-2-6-17(19)18-7-4-5-9-20(18)23/h2-13H,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
4SC AG Curated by ChEMBL					Assay Description Inhibition of cloned Kv1.3 channel (unknown origin) expressed in mammalian cells by whole cell patch clamp assay				Bioorg Med Chem Lett 19: 2299-304 (2009) Article DOI: 10.1016/j.bmcl.2009.02.077 BindingDB Entry DOI: 10.7270/Q29K4B38
					More data for this Ligand-Target Pair