null

SMILES: Fc1ccc(cc1)C(=O)CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2

InChI Key: InChIKey=OYDHYNPQPQRMCX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50279278 ((1R,5S)-3-[2-(4-Fluoro-phenyl)-2-oxo-ethyl]-1,2,3,...) Show SMILES Fc1ccc(cc1)C(=O)CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r| Show InChI InChI=1S/C19H19FN2O2/c20-16-6-4-14(5-7-16)18(23)12-21-9-13-8-15(11-21)17-2-1-3-19(24)22(17)10-13/h1-7,13,15H,8-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50279278 ((1R,5S)-3-[2-(4-Fluoro-phenyl)-2-oxo-ethyl]-1,2,3,...) Show SMILES Fc1ccc(cc1)C(=O)CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r| Show InChI InChI=1S/C19H19FN2O2/c20-16-6-4-14(5-7-16)18(23)12-21-9-13-8-15(11-21)17-2-1-3-19(24)22(17)10-13/h1-7,13,15H,8-12H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	409	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair