null

SMILES: Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2

InChI Key: InChIKey=AHYIHKOHMXQFAV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50279280 (1-(4-Fluorophenyl)-3-(cytisin-12-yl)-1-propanone |...) Show SMILES Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r| Show InChI InChI=1S/C20H21FN2O2/c21-17-6-4-15(5-7-17)19(24)8-9-22-11-14-10-16(13-22)18-2-1-3-20(25)23(18)12-14/h1-7,14,16H,8-13H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50279280 (1-(4-Fluorophenyl)-3-(cytisin-12-yl)-1-propanone |...) Show SMILES Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r| Show InChI InChI=1S/C20H21FN2O2/c21-17-6-4-15(5-7-17)19(24)8-9-22-11-14-10-16(13-22)18-2-1-3-20(25)23(18)12-14/h1-7,14,16H,8-13H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50279280 (1-(4-Fluorophenyl)-3-(cytisin-12-yl)-1-propanone |...) Show SMILES Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r| Show InChI InChI=1S/C20H21FN2O2/c21-17-6-4-15(5-7-17)19(24)8-9-22-11-14-10-16(13-22)18-2-1-3-20(25)23(18)12-14/h1-7,14,16H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Genova Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates				J Med Chem 52: 4345-57 (2009) Article DOI: 10.1021/jm900225j BindingDB Entry DOI: 10.7270/Q2K64J03
					More data for this Ligand-Target Pair