BDBM50279456 1-(2,3-dihydro-6-methylchromen-4-ylideneamino)-3-(3-(4-methylpiperazin-1-yl)propyl)imidazolidine-2,4-dione::CHEMBL518889

SMILES: CN1CCN(CCCn2c(O)cn(N=C3CCOc4ccc(C)cc34)c2=O)CC1

InChI Key: InChIKey=MBXZOOSMUBCUAV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Cavia porcellus)	BDBM50279456 (1-(2,3-dihydro-6-methylchromen-4-ylideneamino)-3-(...) Show SMILES CN1CCN(CCCn2c(O)cn(N=C3CCOc4ccc(C)cc34)c2=O)CC1 |w:13.12| Show InChI InChI=1S/C21H29N5O3/c1-16-4-5-19-17(14-16)18(6-13-29-19)22-26-15-20(27)25(21(26)28)8-3-7-24-11-9-23(2)10-12-24/h4-5,14-15,27H,3,6-13H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	619	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...				Bioorg Med Chem Lett 19: 1477-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.022 BindingDB Entry DOI: 10.7270/Q22J6BQK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 1 (Cavia porcellus)	BDBM50279456 (1-(2,3-dihydro-6-methylchromen-4-ylideneamino)-3-(...) Show SMILES CN1CCN(CCCn2c(O)cn(N=C3CCOc4ccc(C)cc34)c2=O)CC1 |w:13.12| Show InChI InChI=1S/C21H29N5O3/c1-16-4-5-19-17(14-16)18(6-13-29-19)22-26-15-20(27)25(21(26)28)8-3-7-24-11-9-23(2)10-12-24/h4-5,14-15,27H,3,6-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...				Bioorg Med Chem Lett 19: 1477-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.022 BindingDB Entry DOI: 10.7270/Q22J6BQK
					More data for this Ligand-Target Pair