BDBM50279478 4-(2,6-dichlorophenyl)-9-hydroxy-6-(3-morpholino-3-oxopropyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL486101

SMILES: Oc1ccc2n(CCC(=O)N3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1c(Cl)cccc1Cl

InChI Key: InChIKey=UVJHXOMIDQIKET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279478 (4-(2,6-dichlorophenyl)-9-hydroxy-6-(3-morpholino-3...) Show SMILES Oc1ccc2n(CCC(=O)N3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1c(Cl)cccc1Cl |(-1.49,.05,;-.28,-.9,;-.49,-2.43,;.72,-3.38,;2.15,-2.8,;3.54,-3.48,;3.57,-5.02,;2.25,-5.81,;2.28,-7.35,;3.63,-8.09,;.96,-8.15,;-.38,-7.39,;-1.69,-8.18,;-1.67,-9.72,;-.32,-10.47,;1,-9.68,;4.66,-2.43,;6.21,-2.44,;6.99,-1.1,;6.21,.24,;6.7,1.7,;8.16,2.17,;5.46,2.61,;4.21,1.72,;2.75,2.2,;4.68,.25,;3.9,-1.08,;2.36,-1.26,;1.14,-.32,;8.52,-1.1,;9.29,-2.44,;8.52,-3.77,;10.83,-2.44,;11.6,-1.11,;10.83,.23,;9.29,.23,;8.52,1.56,)| Show InChI InChI=1S/C27H21Cl2N3O5/c28-17-2-1-3-18(29)22(17)16-13-20-23(25-24(16)26(35)30-27(25)36)15-12-14(33)4-5-19(15)32(20)7-6-21(34)31-8-10-37-11-9-31/h1-5,12-13,33H,6-11H2,(H,30,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair