BDBM50279479 6-(3-(1H-imidazol-1-yl)-3-oxopropyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL488571

SMILES: Oc1ccc2n(CCC(=O)n3ccnc3)c3ccc4C(=O)NC(=O)c4c3c2c1

InChI Key: InChIKey=XQRYZSMUIDBFFU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279479   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279479 (6-(3-(1H-imidazol-1-yl)-3-oxopropyl)-9-hydroxypyrr...) Show SMILES Oc1ccc2n(CCC(=O)n3ccnc3)c3ccc4C(=O)NC(=O)c4c3c2c1 Show InChI InChI=1S/C20H14N4O4/c25-11-1-3-14-13(9-11)17-15(4-2-12-18(17)20(28)22-19(12)27)24(14)7-5-16(26)23-8-6-21-10-23/h1-4,6,8-10,25H,5,7H2,(H,22,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair