BDBM50279494 6-(3-(1H-imidazol-1-yl)-3-oxopropyl)-4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL520537

SMILES: Oc1ccc2n(CCC(=O)n3ccnc3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl

InChI Key: InChIKey=ZPEXGRAEJXKPDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279494 (6-(3-(1H-imidazol-1-yl)-3-oxopropyl)-4-(2-chloroph...) Show SMILES Oc1ccc2n(CCC(=O)n3ccnc3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl Show InChI InChI=1S/C26H17ClN4O4/c27-18-4-2-1-3-15(18)16-12-20-22(24-23(16)25(34)29-26(24)35)17-11-14(32)5-6-19(17)31(20)9-7-21(33)30-10-8-28-13-30/h1-6,8,10-13,32H,7,9H2,(H,29,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair