BDBM50279495 6-(3-(1H-imidazol-1-yl)-3-oxopropyl)-4-(2,6-dichlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL486728

SMILES: Oc1ccc2n(CCC(=O)n3ccnc3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1c(Cl)cccc1Cl

InChI Key: InChIKey=FMPDOWUVELLXDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279495 (6-(3-(1H-imidazol-1-yl)-3-oxopropyl)-4-(2,6-dichlo...) Show SMILES Oc1ccc2n(CCC(=O)n3ccnc3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1c(Cl)cccc1Cl |(13.54,.17,;14.74,-.8,;14.5,-2.33,;15.7,-3.29,;17.13,-2.74,;18.52,-3.44,;18.54,-4.98,;17.23,-5.77,;17.25,-7.31,;18.6,-8.06,;15.93,-8.11,;14.52,-7.51,;13.51,-8.67,;14.31,-9.99,;15.81,-9.65,;19.65,-2.41,;21.2,-2.44,;22,-1.12,;21.25,.24,;21.75,1.69,;23.23,2.13,;20.53,2.62,;19.27,1.74,;17.82,2.25,;19.71,.27,;18.91,-1.05,;17.37,-1.2,;16.17,-.24,;23.54,-1.15,;24.28,-2.5,;23.49,-3.81,;25.82,-2.53,;26.62,-1.2,;25.86,.15,;24.33,.17,;23.58,1.51,)| Show InChI InChI=1S/C26H16Cl2N4O4/c27-16-2-1-3-17(28)21(16)15-11-19-22(24-23(15)25(35)30-26(24)36)14-10-13(33)4-5-18(14)32(19)8-6-20(34)31-9-7-29-12-31/h1-5,7,9-12,33H,6,8H2,(H,30,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair