BDBM50279537 9-hydroxy-6-(3-(4-methylpiperazin-1-yl)propyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL483953

SMILES: CN1CCN(CCCn2c3ccc(O)cc3c3c4C(=O)NC(=O)c4ccc23)CC1

InChI Key: InChIKey=UGTRDRXYGKOXBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50279537 (9-hydroxy-6-(3-(4-methylpiperazin-1-yl)propyl)pyrr...) Show SMILES CN1CCN(CCCn2c3ccc(O)cc3c3c4C(=O)NC(=O)c4ccc23)CC1 Show InChI InChI=1S/C22H24N4O3/c1-24-9-11-25(12-10-24)7-2-8-26-17-5-3-14(27)13-16(17)19-18(26)6-4-15-20(19)22(29)23-21(15)28/h3-6,13,27H,2,7-12H2,1H3,(H,23,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair